Outcome of COVID-19 in Patients Requiring Haemodialysis- A Retrospective Observational Study
Published: November 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/51889.15613
Girish P Vakrani, Tanuja Nambakam
1. Associate Professor, Department of Nephrology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India.
2. Professor, Department of General Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India.
Correspondence
Dr. Girish P Vakrani,
'A' Block, No. 29, Vydehi Hospital Staff Quarters #82, EPIP Area Whitefield, Bangalore-560066, Karnataka, India.
E-mail: drvakranis@gmail.com
Introduction: Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) are risk factors for COVID-19 infection. Patients with kidney disease also have other co-morbidities like hypertension, diabetes mellitus, cardiovascular disease that are risk factors for poor outcome in COVID-19 infections. Severe COVID-19 has multiorgan involvement including AKI. Compared to normal population, renal failure patients with COVID-19 have extensive lung involvement, need more ventilator support, and have higher mortality.
Aim: To assess outcome (mortality, recovery) and association between factors (age, gender, co-morbidities), biochemical parameters with mortality in COVID-19 patients requiring haemodialysis.
Materials and Methods: It was a retrospective observational study wherein, data was collected, entered and analysed with Statistical Package for the Social Sciences (SPSS) version 19.0 using medical records of all COVID-19 patients who had renal failure (AKI or CKD) requiring haemodialysis. The study period was from June-September 2020 at Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India.
Results: Out of total 68 COVID-19 positive patients, mean age of presentation was 55.08 years and with 75% of the study population were males. Most patients presented with severe COVID-19 illness with tachypnoea and hypoxia. The AKI occurrence and mortality was noted in 44.1% and 47%, respectively. It was noted that medication usage was higher for corticosteroids, oseltamivir, vitamin C, zinc therapy.
Conclusion: In the present single centre study involving COVID19 patients requiring haemodialysis, it was noticed that severe COVID-19 illness, presence of AKI, chronic respiratory illness and high inflammatory markers were associated with higher mortality.
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